With Real Intent

The God question

What Prayer Has Cured

Vaccines ended or nearly ended diseases that killed American children by the thousands. The best-built test of prayer for the sick found no benefit beyond the medicine.

The point in one sentence

James promises that “the prayer of faith shall save the sick.” The best controlled test of that promise followed 1,802 heart bypass patients. Intercessory prayer, which means praying for someone else, made no difference to their complications. Over the same century, a worldwide vaccination and surveillance campaign took smallpox off the earth, and in the United States vaccines cut disease after disease by 95.7 to 100 percent.

Three former directors of the Global Smallpox Eradication Program at the CDC, 1980. Left to right: J. Donald Millar, William H. Foege and J. Michael Lane. The magazine they hold is World Health, May 1980. The cover reads “smallpox is dead!” The CDC describes the photo as showing them reading “the good news that smallpox had been eradicated on a global scale.” Public domain, CDC. Image via Wikimedia Commons.

The world this promise came from

If you grew up in the Church, you know what it is to be sick and to be prayed for. Two elders come to the bedroom. They anoint with consecrated oil, lay their hands on the person’s head, and give a blessing. A name may go on the temple prayer roll. Nobody who has watched a family do this thinks it is empty. It comes from love, and it is one of the most tender things the Church does.

It rests on two passages you may have heard in a lesson. The first is in the Bible, and the second is in the Doctrine and Covenants, the book of revelations to Joseph Smith.

What the scriptures and the Church say

James 5:14–15, King James Version

“Is any sick among you? let him call for the elders of the church; and let them pray over him, anointing him with oil in the name of the Lord: And the prayer of faith shall save the sick, and the Lord shall raise him up; and if he have committed sins, they shall be forgiven him.”

This is the passage behind priesthood blessings of the sick. Notice the verb. It does not say “may comfort” or “may help.” It says shall save.

James 5, KJV

Doctrine and Covenants 42:43–44, 48, in your scriptures today

“And whosoever among you are sick, and have not faith to be healed, but believe, shall be nourished with all tenderness, with herbs and mild food, and that not by the hand of an enemy. And the elders of the church, two or more, shall be called, and shall pray for and lay their hands upon them in my name; and if they die they shall die unto me, and if they live they shall live unto me.” … “And again, it shall come to pass that he that hath faith in me to be healed, and is not appointed unto death, shall be healed.”

Three things are here. Verse 43 is written for the sick who “have not faith to be healed, but believe,” and it tells them to be cared for with tenderness, herbs and mild food. That is the believing answer at its strongest (see below). Verse 44 sends for the elders. And verse 48 attaches a condition to the promise: healed if you have faith “and [are] not appointed unto death.”

D&C 42, on churchofjesuschrist.org

The Church’s General Handbook, section 18.13, “Administering to the Sick”

“Usually, administering to the sick should be done at the request of the person receiving the blessing or at the request of others who are concerned so the blessing will be according to their faith.”

The handbook is the Church’s rulebook for leaders. This section is about how a blessing is given. It ties the blessing to the faith of those who ask.

General Handbook, chapter 18

Elder Dallin H. Oaks, “Healing the Sick,” priesthood session, April 2010 General Conference

“Latter-day Saints believe in applying the best available scientific knowledge and techniques. … The use of medical science is not at odds with our prayers of faith and our reliance on priesthood blessings.”

This is the Church’s teaching on how faith and medicine fit together. Elder Oaks goes on to quote Brigham Young: “It appears consistent to me to apply every remedy that comes within the range of my knowledge, and [then] to ask my Father in Heaven… to sanctify that application to the healing of my body.”

The talk, on churchofjesuschrist.org

The Church teaches both: pray and get the best medicine. The question is what the prayer adds.

Medicine can be counted. So can prayer. Both have been counted.

From the scripture to the evidence

The promise is old. The tests are recent. Every date below is sourced on this page.

1977
The last known natural case of smallpox, in Somalia. In 1980 the World Health Organization declared smallpox eradicated, after years of worldwide immunization and surveillance.
1988
The first of two small hospital studies reports benefit from prayer: 393 coronary-care patients, a lower severity score for the 192 who were prayed for (Byrd).
1998
A study in Pediatrics counts 172 children who died in families from groups that rely on faith healing instead of medicine (Asser and Swan).
1999
A second small study, 990 patients, reports a lower score for the prayed-for group on a hospital scoring scale (Harris).
2006
The STEP trial, 1,802 heart bypass patients in six hospitals. “Intercessory prayer itself had no effect on complication-free recovery from CABG.”
2009
The Cochrane review pools 10 trials and 7,646 patients: “no clear effect of intercessory prayer on death.”
2010
Elder Oaks teaches that medical science “is not at odds” with prayers of faith and blessings.
2021
The First Presidency: “We urge individuals to be vaccinated. Available vaccines have proven to be both safe and effective.”

Sources: WHO; Byrd 1988; Asser and Swan 1998; Harris 1999; Benson 2006; Roberts 2009; Oaks 2010; First Presidency statement, August 12, 2021, as reported by KSL

The exhibits

Here is what the best studies found, in the researchers’ own words.

Exhibit A

Benson and colleagues, STEP trial, American Heart Journal, April 2006

1,802 patients, 6 hospitals

“Intercessory prayer itself had no effect on complication-free recovery from CABG, but certainty of receiving intercessory prayer was associated with a higher incidence of complications.”

What it establishes: A large, randomized test of prayer for the sick. CABG is bypass surgery. The study tested whether other people praying for a patient changed how the patient did after surgery. It did not.

The abstract, on PubMed
Exhibit B

Same abstract, the numbers

2006

“Complications occurred in 52% (315/604) of patients who received intercessory prayer versus 51% (304/597) of those who did not.” And: “Complications occurred in 59% (352/601) of patients certain of receiving intercessory prayer compared with the 52% (315/604) of those uncertain.”

What it establishes: Compare the first two numbers. 52 percent of the prayed-for patients had complications, and 51 percent of the others. The prayed-for group did one point worse. The authors report that major events and 30-day death rates were similar across all three groups. The abstract reports the 59 percent figure and does not say why.

Same abstract
Exhibit C

Roberts, Ahmed, Hall and Davison, Cochrane Database of Systematic Reviews, 2009

10 trials, 7,646 patients

“For the comparison of intercessory prayer plus standard care versus standard care alone, overall there was no clear effect of intercessory prayer on death.” … “These findings are equivocal and, although some of the results of individual studies suggest a positive effect of intercessory prayer, the majority do not.”

What it establishes: Cochrane is a group of scientists who collect every good trial on a question and add up the results. The pooled answer: no clear effect on death. It also says the evidence does not support a recommendation “either in favour or against the use of intercessory prayer.” That is as far as these trials can go.

The abstract, on PubMed
Exhibit D

Byrd, Southern Medical Journal, 1988, and Harris and colleagues, Archives of Internal Medicine, 1999

The two studies that favored prayer

Byrd: 393 patients (192 prayed for, 201 not), with a “significantly lower severity score” in the prayed-for group. Harris: 990 patients (466 prayed for, 524 usual care), lower scores for the prayed-for group, and the authors conclude “prayer may be an effective adjunct to standard medical care.”

What it establishes: This is the strongest evidence on the other side, and it is stated in full. Both used scoring systems, not deaths or cures. The 2006 trial, more than four times the size of the 1988 study and nearly twice the size of the 1999 one, did not confirm it.

Harris 1999, PubMed

In the STEP trial, patients were randomly placed in one of three groups, and prayer was provided for two of the groups for 14 days, beginning before surgery. It was prayer by other people, not a blessing given at the sick person’s own request.

The column that is full

Now the other side of the ledger. These are numbers from the CDC’s own count, in a 1999 CDC report, Achievements in Public Health, 1900–1999: Impact of Vaccines Universally Recommended for Children, United States, 1990–1998. It compares each disease’s yearly cases in the years just before its vaccine (a different span for each disease) with the 1998 count, in the United States. The bars below are drawn on true scale: the top bar is 100 percent, a disease that is completely gone.

How far vaccines cut each disease in the United States

Percent drop from the yearly cases before each vaccine to the 1998 count. The top bar is the whole: 100 percent.

A disease completely gone (the whole)100%
Smallpox (48,164 a year to 0)100%
Polio, paralytic (16,316 to 0; one vaccine-associated case not counted)100%
Diphtheria (175,885 to 1)about 100%
Measles (503,282 to 89)about 100%
Haemophilus influenzae type b (20,000 to 54)99.7%
Mumps (152,209 to 606)99.6%
Rubella (47,745 to 345)99.3%
Tetanus (1,314 to 34)97.4%
Whooping cough (147,271 to 6,279)95.7%

Source: CDC, MMWR, “Achievements in Public Health, 1900–1999: Impact of Vaccines Universally Recommended for Children,” 1999, Table 2. US figures; 1998 counts are provisional. Tetanus and Hib baselines are CDC estimates; the mumps baseline is its first reporting year, 1968.

The baselines, by disease: smallpox, the yearly average for 1900–1904. Diphtheria, 1920–1922, three years before its vaccine. Whooping cough, 1922–1925, four years before. Tetanus, 1922–1926, estimated from deaths. Polio, 1951–1954, four years before licensure. Measles, 1958–1962, five years before. Mumps, 1968. Rubella, 1966–1968, three years before. Hib, an estimate from surveillance studies before the 1985 vaccine.

Smallpox is the one that is gone from the whole earth, declared eradicated by the WHO in 1980 after years of worldwide immunization and surveillance. The WHO says “the last known natural case was in Somalia in 1977,” and that it was “fatal in up to 30% of cases.” The CDC puts it plainly: about 3 out of every 10 people who got it died.

A boy with polio, at Herman Kiefer Hospital in Detroit, in an Emerson respirator, an “iron lung,” about 1955. The machine breathed for children whose breathing muscles were paralyzed. The WHO says one in 200 polio infections leads to irreversible paralysis, and that among those paralysed, “5–10% die when their breathing muscles become immobilized.” Photo: National Museum of Health and Medicine (NCP 4145), Herman Kiefer Hospital, Detroit, about 1955, CC BY 2.0. Resized from the original. Image via Wikimedia Commons.

The WHO says that cases of wild polio have “decreased by over 99% since 1988, from an estimated 350 000 cases in more than 125 endemic countries, to two endemic countries” (WHO fact sheet, April 2, 2025). Add it all up across 50 years, and a 2024 study in The Lancet estimated that vaccination “has averted 154 million deaths,” 101 million of them infants. That is a model, not a count, and the authors present it as an estimate.

Measles shows what these numbers meant for families. Before the vaccine, the CDC says, 3 to 4 million Americans were infected every year, 48,000 were hospitalized, and 400 to 500 died. The Health Claims page has more on this: Health Claims and the Same Test.

What medicine counted, and what the prayer tests counted

What medicine has measurably done
  • Smallpox: gone from the earth, declared eradicated by the WHO in 1980.
  • Polio: wild cases down more than 99 percent since 1988.
  • Diphtheria, measles, mumps, rubella, tetanus, whooping cough: down 95.7 to about 100 percent in the US.
  • Every result counted in the CDC’s numbers, open for anyone to check.
What the prayer trials found
  • STEP, 1,802 patients: “no effect on complication-free recovery.”
  • Complications: 52 percent with prayer, 51 percent without.
  • Cochrane, 10 trials, 7,646 patients: “no clear effect of intercessory prayer on death.”
  • The two small studies that favored prayer used scoring systems, and the larger test did not confirm them.

Here is how the STEP trial worked.

1,802 heart bypass patients were randomly assigned to one of three groups.Random assignment means the groups are alike at the start, so any difference at the end comes from what was done.
Group 1 (604 patients) was prayed for and was told only that they might be.Prayer lasted 14 days, starting before surgery.
Group 2 (597) was not prayed for and was told the same.Groups 1 and 2 are the prayer-versus-no-prayer comparison.
Group 3 (601) was prayed for and was told for certain.This group tests what knowing about the prayer does.
Result: 52 percent, 51 percent, 59 percent had complications.Prayer made no difference in the first two. The group told for certain that they were being prayed for did worse (59 percent) than the prayed-for group that was not told (52 percent). The authors report that major events and 30-day death rates were similar across all three groups.

The STEP trial, on true scale

Share of patients with complications after bypass surgery, out of 100 percent.

Everyone (the whole)100%
Prayed for, not told for certain (315 of 604)52%
Not prayed for, not told (304 of 597)51%
Prayed for, and told for certain (352 of 601)59%

Source: Benson and colleagues, American Heart Journal, 2006;151(4):934-42. Only the first two rows are the prayer-versus-no-prayer comparison.

What is true on the other side

The strongest believing answer is not “prayer is magic.” It is what Elder Oaks teaches, and what D&C 42 itself says. It is worth hearing at its full strength.

All of that can be true, and it leaves two things standing.

First, prayer adds nothing that can be measured beyond the medicine. In the STEP trial every patient had surgery and the best hospital care. The only difference was the prayer. The difference in complications was 52 percent against 51 percent, which the authors counted as no effect.

Second, the promise in the text is a different promise. James says the prayer of faith “shall save the sick.” D&C 42:48 says that one with faith “shall be healed.” If prayer is for comfort and trust, then that is not what these verses say.

A promise that fits every outcome cannot be tested.

At a funeral Elder Oaks’s cousin said: “I know that there is enough faith in this family that she would have been healed unless it was the will of the Lord to take her home at this time.” Elder Oaks said such teachings ring true to him: “We do all that we can for the healing of a loved one, and then we trust in the Lord for the outcome.” That is a faith that can hold up through a death. It is also a promise no result can count against: if the patient lives, the promise worked, and if the patient dies, it was the Lord’s will.

A fact about the claim The STEP trial and the Cochrane review do not show that prayer is harmful. They show that other people praying for a patient did not improve the patient’s results. The 59 percent figure comes from patients who were told for certain they would be prayed for. The abstract does not say why, and nothing here claims prayer caused it.

When prayer is used instead of medicine

Praying and getting treatment together takes nothing from the patient. The harm comes when prayer takes the place of treatment. The best-known study of this is a 1998 report in Pediatrics by Seth Asser and Rita Swan. They looked at 172 children who died between 1975 and 1995 in families from religious groups that rely on faith healing instead of medicine. Their finding:

Asser and Swan, “Child fatalities from religion-motivated medical neglect,” Pediatrics, April 1998

“One hundred forty fatalities were from conditions for which survival rates with medical care would have exceeded 90%.” Eighteen more had expected survival rates above 50 percent.

So for 140 of the 172 children, the authors estimated that a child with that condition survives more than 90 percent of the time with medical care. For 18 more the estimate was better than even odds. The abstract calls them “faith-healing sects” and does not name the groups, so this page does not say which they were. The Church teaches the opposite: Elder Oaks says medical science “is not at odds” with blessings, and the First Presidency urged vaccination in 2021.

The abstract, on PubMed

140 of 172 children died of conditions that, by the authors’ estimate, children survive more than 90 percent of the time with medical care. Source: Asser and Swan, Pediatrics, 1998.

The study does not say these parents were careless, and nothing in it says they were reading James 5. What it shows is what happens when prayer takes the place of the doctor: the children died of conditions medicine usually treats.

The common rebuttals

“God works through doctors. The vaccine is the answer to the prayer.”

This is what the Church itself teaches, and it may be how it feels from the inside. But look at what it admits. If the answer always arrives as medicine, and the prayer adds nothing the trials can find, then the work you can measure is the work of the researchers and the nurses. In the STEP trial, every patient got the medicine. The only difference was the prayer, and it made no difference to complications. And James does not say “God will work through the doctor.” He says the prayer of faith “shall save the sick.”

“Vaccines prevent. Prayer heals. They are different.”

That is fair. Nobody prays to prevent smallpox. That is why the page does not rest on the vaccine column alone. STEP and the Cochrane review tested healing directly: patients who were already sick or facing heart surgery, prayed for or not. The vaccine column shows what happens when a remedy is tested and works. The trial column shows what happens when prayer gets the same kind of test.

“You cannot test God.”

Nobody tested God. They tested the claim that people praying for a patient changes how the patient does. That claim is in the text, and it is a claim about sick people, who can be counted. If the answer to every result is “that was the Lord’s will,” then the claim cannot fail, and a claim that cannot fail has nothing to say about whether to pray.

“I have seen a healing myself.”

You may have, and the relief was real. Most illnesses get better on their own, and people pray hardest when things are worst, so recoveries follow prayers whether or not the prayer does anything. That is why a trial compares a group that was prayed for with a group that was not. When that comparison was made on 1,802 patients, the prayed-for and not-prayed-for groups had the same rate of complications. Read more about how feelings and experiences are tested on How We Know Things, Believing Without Evidence, and The Case Against the God You Were Taught.

“A blessing is for comfort, not for cure.”

That is a fair thing to believe, and it is the version that survives. But it is not what the verse says, and a family that reads the verse as written is entitled to expect it. If comfort is the purpose, say so, and keep the doctor in the room.

Every disease on the list fell to something that could be tested, measured, and given to everyone.

No controlled test has shown a disease giving way to prayer beyond what the medicine did.

What this means

You saw three things. Smallpox, a disease that killed up to 3 in 10 people, is gone, and the CDC’s own table shows polio, diphtheria and measles down by about 100 percent in the US. The best-built test of prayer for the sick, 1,802 patients, found no effect on complications, and the pooled review of 10 trials found no clear effect on death. And among 172 children who died in families that relied on faith healing instead of medicine, 140 died of conditions that, by the authors’ estimate, children survive more than 9 times out of 10 when they get medical care.

The promise says “shall save the sick.” Medicine ended these diseases. The prayer was tested alongside the medicine and added nothing anyone could find.

That is the finding, stated as exactly as it can be. The best-built test of prayer for the sick found no effect, and the Cochrane review of 10 trials found no clear effect on death. Two small early studies reported a benefit; the larger, better-built tests that followed did not find one. James 5:15 does not promise a small score difference. It promises that “the prayer of faith shall save the sick.” James wrote it as if it were certain. The question the evidence leaves is who made that promise, and why.

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